NF2
neurofibromin 2 (merlin)
Sinónimos:
ACN, BANF, SCH
Especie:
Human NF2 (4771), Mouse Nf2 (18016), Rat Nf2 (25744), chicken NF2 (395158), domestic cat NF2 (101087787), dog NF2 (477535), cow NF2 (540479), Horse NF2 (100058977), Domestic Rabbit NF2 (100357691), sheep NF2 (101107995) ...Más
ID UniProtKB:
ID del gen:
- Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
- Mouse(18016) neurofibromatosis 2
- Rat(25744) neurofibromin 2 (merlin)
- chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
- domestic cat(101087787) neurofibromin 2 (merlin)
- dog(477535) neurofibromin 2 (merlin)
- cow(540479) neurofibromin 2 (merlin)
- Horse(100058977) neurofibromin 2 (merlin)
- Domestic Rabbit(100357691) neurofibromin 2 (merlin)
- sheep(101107995) neurofibromin 2 (merlin)
- naked mole-rat(101706100) neurofibromin 2 (merlin)
- domestic guinea pig(100715365) neurofibromin 2 (merlin)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
KD-Validated Anti NF2 / Merlin Antibody, clone 23GB2620, Rabbit Monoclonal, clone 23GB2620, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
ANTI-MERLIN(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Merlin Antibody, clone 1H15-L1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
affinity binding assay
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti- NF2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
Número de producto
Descripción
Especie