Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

711624

Sigma-Aldrich

1,3-Diiodo-5,5-dimethylhydantoin

≥96%

Synonym(s):

DIH

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C5H6I2N2O2
CAS Number:
Molecular Weight:
379.92
Beilstein:
146040
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

Assay

≥96%

form

powder

storage temp.

−20°C

SMILES string

CC1(C)N(I)C(=O)N(I)C1=O

InChI

1S/C5H6I2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3

InChI key

RDZHCKRAHUPIFK-UHFFFAOYSA-N

Application

DIH - Highly efficient and economical reagent for Iodination

Used for:
  • Preparation of nitriles from corresponding alcohols and amines via oxidative conversion
  • Chemoselective, stereospecific iododesilylation of silylated alkenes
  • Preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes with toluenesulfonamide in presence of diiododimethylhydantoin
  • Iodination reactions

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Ox. Sol. 2 - Skin Corr. 1B

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rui Sun et al.
Psychophysiology, 58(2), e13731-e13731 (2020-12-08)
Neurophysiological investigation of neural processes are hindered by the presence of large artifacts associated with eye movement. Although blind source separation (BSS)-based hybrid algorithms are useful for separating, identifying, and removing these artifacts from EEG, it remains unexamined to what
Miguel Perez-Aso et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(1), 457-465 (2015-09-30)
Ionizing radiation is a common therapeutic modality and following irradiation dermal changes, including fibrosis and atrophy, may lead to permanent changes. We have previously demonstrated that occupancy of A2A receptor (A2AR) stimulates collagen production, so we determined whether blockade or
Yani Zhao et al.
PloS one, 6(12), e29624-e29624 (2012-01-05)
The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells. Recent evidence suggests that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recruitment. However
Shirin Sabouri et al.
Journal of magnetic resonance imaging : JMRI, 46(3), 861-869 (2017-01-29)
To determine the relationship between parameters measured from luminal water imaging (LWI), a new magnetic resonance imaging (MRI) T In all, 17 patients with prostate cancer were examined with a 3D multiecho spin echo sequence at 3T prior to undergoing
Pamela M Vacek et al.
Occupational and environmental medicine, 74(3), 211-217 (2016-11-09)
To understand why 2 studies relating crystalline silica exposure to lung-cancer mortality in Vermont granite workers yielded conflicting results. Data used in the 2 studies were linked to identify discrepancies. Mortality data and employment histories from the earlier study were

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service