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Key Documents

230553

Sigma-Aldrich

Sodium ethoxide solution

21 wt. % in ethanol

Synonym(s):

Sodium ethylate

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About This Item

Linear Formula:
CH3CH2ONa
CAS Number:
Molecular Weight:
68.05
Beilstein:
3593646
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

form

liquid

Quality Level

concentration

21 wt. % in ethanol

refractive index

n20/D 1.385

density

0.868 g/mL at 25 °C

SMILES string

[Na+].CC[O-]

InChI

1S/C2H5O.Na/c1-2-3;/h2H2,1H3;/q-1;+1

InChI key

QDRKDTQENPPHOJ-UHFFFAOYSA-N

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General description

Sodium ethoxide is an alkoxide salt mainly used as a strong base in organic reactions such as deprotonation, dehydration and dehalogenation.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 2 - Self-heat. 1 - Skin Corr. 1A - STOT SE 2

Target Organs

Eyes,Central nervous system

Supplementary Hazards

Storage Class Code

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 1

Flash Point(F)

48.2 °F - closed cup

Flash Point(C)

9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sodium Ethoxide
Whitaker KS and Whitaker DT
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
Franklin R Tay et al.
Journal of endodontics, 31(8), 593-598 (2005-07-27)
Polycaprolactone, a thermoplastic aliphatic polyester, is reportedly susceptible to both alkaline and enzymatic hydrolyzes. This screening study examined the susceptibility of Resilon, a polycaprolactone-based root filling composite, to alkaline hydrolysis. There were 15-mm diameter disks of Resilon and Obtura gutta-percha
N C Luu et al.
Chemical research in toxicology, 13(7), 610-615 (2000-07-18)
Glutathione conjugate formation plays important roles in the detoxification and bioactivation of xenobiotics. A range of nephrotoxic haloalkenes undergo bioactivation that involves glutathione and cysteine S-conjugate formation. The cysteine S-conjugates thus formed may undergo cysteine conjugate beta-lyase-catalyzed biotransformation to form
Zhao Cai et al.
Applied immunohistochemistry & molecular morphology : AIMM, 13(3), 292-294 (2005-08-06)
The authors describe a simple and cost-effective method of immunostaining semithin epoxy resin sections of peripheral nerve for light microscopy with antibodies to myelin protein zero, peripheral myelin protein 22, myelin basic protein, and neurofilament protein 200 using a combined
E D Clarkson et al.
Clinical chemistry, 44(2), 287-292 (1998-02-25)
A sensitive method is described to detect isolysergic acid diethylamide (iso-LSD) in urine. The compound was extracted from urine and converted to a C-8 carbanion by sodium ethoxide in ethanol. Protonation of the carbanion by water selectively produced LSD. The

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