N0905005
Nitrendipine impurity A
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
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About This Item
Empirical Formula (Hill Notation):
C18H18N2O6
CAS Number:
Molecular Weight:
358.35
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
nitrendipine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C18H18N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9H,5H2,1-4H3
InChI key
YEHVABIPGJLMET-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Nitrendipine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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G R Aronoff
Journal of cardiovascular pharmacology, 6 Suppl 7, S974-S976 (1984-01-01)
To determine the effect of decreased renal function on the elimination kinetics of the calcium entry blocker nitrendipine and its metabolite, we gave 18 subjects with various levels of renal dysfunction a single 20-mg oral dose of nitrendipine. Plasma nitrendipine
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