Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

PHR1686

Supelco

Tazobactam

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Tazobactam, (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo-[3.2.0]heptanes-2-carboxylicacid-4,4-dioxide, [2S-(2α,3β,5α)]-3-Methyl-7-oxo-3-(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsäure-4,4-dioxid

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C10H12N4O5S
CAS Number:
Molecular Weight:
300.29
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1643383

API family

tazobactam

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1

InChI key

LPQZKKCYTLCDGQ-WEDXCCLWSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Tazobactam is a penicillanic acid sulfone used in combination with β-lactamase antibiotic as antibacterial to reduce the development of drug-resistant bacteria.

Application

Tazobactam may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6302 in the slot below. This is an example certificate only and may not be the lot that you receive.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7(9), 127-131 (2019)
Simultaneous determination of piperacillin and tazobactam in pharmaceutical formulations by RP-HPLC method
Veni KRP, et al.
Journal of Pharmacy Research, 7(1), 127-131 (2013)
Emily Marsh et al.
Clinica chimica acta; international journal of clinical chemistry, 486, 265-268 (2018-08-18)
Therapeutic drug monitoring is used for aminoglycosides and vancomycin, and has been proposed for β-lactam antibiotics. Clinical blood samples in the ICU are often obtained via an existing vascular catheter rather than fresh needle phlebotomy. If antibiotics had previously been

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service