90718

Fluorescein isothiocyanate–dextran

average M_w 70,000

• Synonym(s): FITC–Dextran 70, FITC–Dextran
• CAS Number: 60842-46-8
• MDL number: MFCD00131092
• UNSPSC Code: 12352201
• NACRES: NA.32

Properties

• biological source: synthetic
• conjugate: FITC conjugate
• form: powder or crystals
• mol wt: average M_w 70,000
• extent of labeling: 0.001-0.020 mol/mol FITC glucose
• fluorescence: λ_ex 493 nm; λ_em 520 nm±5 nm in 0.1 M Tris pH 8.0
• application(s): cell analysis

Description

General description

Fluorescein isothiocyanate–dextran is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. Fluorescein isothiocyanate–dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform., however, it dissolves in DMSO, formamide, and a few other polar organic solvents.

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran has an application of cell analysis, Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. FITC-dextrans are primary source of studying permeability and transport in cells and tissues and can also be a tool for permeability studies of other materials.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable