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form
powder
storage temp.
−20°C
InChI
1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
InChI key
XUMBMVFBXHLACL-UHFFFAOYSA-N
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General description
Melanin is a vital pigment present on the surface structures of vertebrates, which contribute to skin color. It has three forms such as, eumelanin, pheomelanin and neuromelanin. Melanin has cation chelating and redox properties. It is a potent absorbent of light. Melanin functions as a chemoprotective and photoprotective pigment. Mutations in this gene are associated with oculocutaneous albinism, vitiligo, piebaldism and Waardenburg syndrome.
Application
Melanin has been used:
- in spectrophotometry
- to study its effect on reverse transcription polymerase chain reaction (RT-PCR) inhibition and effect of BSA (bovine serum albumin) in overcoming the inhibition
- as an absorber for skin layer in near-infrared tissue spectra
- Raman spectroscopy
Preparation Note
Prepared by oxidation of tyrosine with hydrogen peroxide.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Melanin
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The International Journal of Biochemistry & Cell Biology, 29(11), 1235-1239 (1997)
Bovine serum albumin reverses inhibition of RT-PCR by melanin
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Biotechniques, 25(4), 564-566 (1998)
Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes
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International Immunology, 18(11), 1541-1548 (2006)
Fengmei Zou et al.
Biomedical optics express, 1(3), 748-761 (2011-01-25)
An accurate SO(2) prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least
Justyna M Drewnowska et al.
PloS one, 10(4), e0125428-e0125428 (2015-04-25)
Although melanin is known for protecting living organisms from harmful physical and chemical factors, its synthesis is rarely observed among endospore-forming Bacillus cereus sensu lato. Here, for the first time, we reported that psychrotolerant Bacillus weihenstephanensis from Northeastern Poland can
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