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R9629

Sigma-Aldrich

D-(−)-Ribose

suitable for cell culture, BioReagent

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
50-69-1
Molecular Weight:
150.13
Beilstein:
1723081
EC Number:
200-059-4
MDL number:
MFCD00135453
UNSPSC Code:
12352201
PubChem Substance ID:
24899416
NACRES:
NA.75

biological source

microbial

product line

BioReagent

Assay

≥99% (GC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

88-92 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

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Application

D-(−)-Ribose has been used for microtissue fabrication and in cell culture.

Biochem/physiol Actions

Ribose is an aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. Ribose-5-phosphate supports the biosynthesis of tryptophan and histidine and is a component of the pentose phosphate pathway.

Suitability

This D-ribose has been qualified for use as a supplement in cell culture.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Matthew Walker et al.
Scientific reports, 10(1), 7696-7696 (2020-05-08)
When stretched, cells cultured on 2D substrates share a universal softening and fluidization response that arises from poorly understood remodeling of well-conserved cytoskeletal elements. It is known, however, that the structure and distribution of the cytoskeleton is profoundly influenced by
Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle
West AR, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 304(1), 4-16 (2012)
Pedro Vizán et al.
International journal of cancer, 124(12), 2789-2796 (2009-03-03)
Cell cycle regulation is dependent on multiple cellular and molecular events. Cell proliferation requires metabolic sources for the duplication of DNA and cell size. However, nucleotide reservoirs are not sufficient to support cell duplication and, therefore, biosynthetic pathways should be
Matthew Walker et al.
APL bioengineering, 4(3), 036107-036107 (2020-09-29)
Characterizing the time-dependent mechanical properties of cells is not only necessary to determine how they deform but also to understand how external forces trigger biochemical-signaling cascades to govern their behavior. At present, mechanical properties are largely assessed by applying local
Hyperactive Rac1 drives MAPK-independent proliferation in melanoma by assembly of a mechanosensitive dendritic actin network
Mohan AS, et al.
bioRxiv (2018)
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