Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

T2397

Sigma-Aldrich

Tyrode′s Salts

With sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture

Synonym(s):

Tyrode′s buffer

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

sterility

sterile-filtered

form

liquid

quality

With sodium bicarbonate

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

glucose: 1.0 g/L (Dextro

Dextro)
NaHCO3: 1.0 g/L

shipped in

ambient

General description

Tyrode′s Salts solution is designed to work with mammalian cells. This balanced salt solution can be used for diluting protein components of media of natural origin. Balanced Salt solution plays a role in providing a buffer system to maintain the medium in optimum pH range (7.2-7.6), irrigating and diluting while maintaining the intra- and extracellular osmotic balance. It facilitates the maintenance of normal cell metabolism by giving water and bulk inorganic ions. Balanced Salt solution provides the energy source for cell metabolism by supplying nutrients.

Application

Tyrode′s Salts has been used:
  • to incubate sperms collected from cauda epididymis of rat, mouse, guinea pig, golden hamster and rabbit
  • for the transportation of lower uterine segment (LUS) strips from women
  • for the transportation of Cor.4U human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ivan Kopljar et al.
Journal of pharmacological and toxicological methods, 91, 80-86 (2018-02-09)
Calcium-based screening of hiPS-CMs is a useful preclinical safety evaluation platform with the ability to generate robust signals that facilitates high-throughput screening and data analysis. However, due to the potential inherent toxicities, it is important to understand potential effects of
Penghua Yang et al.
Nature communications, 10(1), 282-282 (2019-01-19)
Failure of neural tube closure results in severe birth defects and can be induced by high glucose levels resulting from maternal diabetes. MARCKS is required for neural tube closure, but the regulation and of its biological activity and function have
Wenlong Zhao et al.
Journal of cellular and molecular medicine, 22(3), 1755-1768 (2017-11-24)
Outer dense fibers (ODFs), as unique accessory structures in mammalian sperm, are considered to play a role in the protection of the sperm tail against shear forces. However, the role and relevant mechanisms of ODFs in modulating sperm motility and
Gregor Seliger et al.
European journal of obstetrics, gynecology, and reproductive biology, 225, 172-180 (2018-05-08)
The purpose of this study was to assess, if the biomechanical properties of the lower uterine segment (LUS) in women with a previous cesarean section (CS) can be determined by ultrasound (US) elastography. The first aim was to establish an
Songying Cao et al.
Cell death & disease, 11(10), 859-859 (2020-10-17)
During mouse embryonic development, vasculogenesis initially occurs in the yolk sac, preceding neurulation. Our previous studies have demonstrated that maternal diabetes induces embryonic vasculopathy at early embryonic developmental stage by suppressing the expression of vascular growth factors including BMP4 (bone

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service