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MilliporeSigma

Custom Peptide Manufacturing

Custom Peptide Libraries configured in a convenient plate format; perfect for screening applications, epitope mapping and peptide microarray production.

Synthetic custom peptides are important tools in drug discovery and proteomic research. Our custom peptide synthesis service portfolio supports researchers in applications requiring high-quality custom peptides, and arrays. In addition to the use of cutting-edge technology, competitive prices, and continuous investment in worldwide operations, we also offer:

  • Deep scientific expertise and over 30 years of experience in the field - we meet customers’ specifications, no matter how complex.
  • Outstanding customer service & technical support - our customers are provided with best-in-class service and support.
  • Our commitment to quality for guaranteed product performance - It is the output of our state-of-the-art analytical instruments, coupled with a robust quality management system. 
ProductProduct Description 
Custom Peptide SynthesisMilligram to gram quantities with a variety of options to meet your research needs. Request Quote

Custom Peptide Synthesis

Please take advantage of our specialized knowledge on sophisticated peptide design, synthesis methods, and handling. We offer a comprehensive service portfolio to support researchers.

Specification 
Peptide Length6~30 amino acid residues(please inquire us for less than 6 residues or more than 31 residues)
Quantity2 mg, 5 mg, 10 mg, 15 mg, 25 mg, 50 mg, 100 mg (for other quantities, please inquire)
Chemical ModificationAcetylation, Biotinylation, Amidation, Ahx, KLH Conjugation, etc.
Labeling DyeFAM, TAMRA
PurityUnpurified, 70%≦, 80%≦, 90%≦, 95%≦

Guidelines for selecting the purity of custom peptides based on their intended use

Please select the desired purity (≦) from the following options. We also offer purity guarantees via HPLC to accommodate various research needs for other purities and synthesis scales. Please feel free to consult with us regarding immunological purity (Crude), 70%≦, 80%≦, 90%≦, and 95%

Purification levelRecommended applications
  • Immunological purity (Crude)
  • 70% purity ≦
  • Immunization of animals and production of antiserum
  • ELISA standards for measuring antibody titers in antiserum
  • 80% purity≦
  • 90% purity≦
  • Non-quantitative enzyme-substrate research
  • Phosphorylation reaction
  • Non-quantitative peptide blocking experiments for Western blotting, immunostaining, and in vitro bioassays
  • Coupling to chromatography resins for affinity purification
  • Coating onto tissue culture plates for cell adhesion
  • ≦95% purity
  • Standard for quantitative ELISA and RIA
  • Quantitative receptor-ligand interaction studies
  • in vitro bioassays
  • in vitro research
  • Enzyme studies
  • Standards for chromatography
  • NMR studies

Peptide dissolution and storage methods

Storage Methods

  • Peptides are delivered in a lyophilized (freeze-dried) state. Upon receiving the peptides, store them in a dark place at 2-8℃ or below this temperature.
  • Lyophilized peptides are stable at room temperature for a few days to weeks, but if you plan to store for a longer period, we recommend storing them at -20℃ or below.
  • Humidity can degrade peptide stability. When using peptides stored in a freezer, ensure they return to room temperature sufficiently before use.

Dissolution Methods

  • There is no universal solvent that can dissolve all lyophilized peptides, but it must be compatible with the biological assay.
  • You may need to try multiple solvents to find the suitable solvent. To select the most appropriate solvent for your peptides, some trial-and-error may be necessary.
  • The first chosen solvent may not work, so it is good to first try solvents that can be easily removed by freeze-drying. Therefore, it is important to perform solubility tests with a small amount of peptide before dissolving all of the peptide.

Related Product Resources

  • Article: Peptide Quick Tips

    Helpful guidelines for proper storage and resuspension of your peptide for optimal performance in your assay.

  • Article: Handling and Storage Protocol for Synthetic Peptides

    One of the most challenging aspects of working with synthetic peptides is determining the best solvent in which to dissolve the peptide. General guidelines for proper storage, handling and dissolving your synthetic peptide are provided.

  • Article: Designing Peptides

    When selecting peptides for custom synthesis, several important factors should be considered during the design process. These considerations include sequence length, solubility and sequence stability.



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