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Upstream Process Chemicals

Worker loading upstream chemicals for bioprocessing

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. You can rely on our cell culture media, purification, and clean-in-place products for consistent performance at every stage, from research to commercial application. Equally important, you can trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service. 

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Emprove® Chemicals for Quality and Regulatory Support

Controlled manufacturing processes, optimized quality attributes, and precise analytical specifications make our raw materials well-suited for commercial biopharma processing. Now they go even further to simplify your qualification and risk assessment, as part of our industry-leading Emprove® Chemicals portfolio. All raw and starting materials are organized into categories to streamline selection, with each product offering the comprehensive, up-to-date documentation you need to navigate regulatory challenges, manage risks, and improve processes.

  • Emprove® Evolve is for early stages of biopharmaceutical manufacturing, bridging the gap between lab-grade and GMP compliant raw and starting materials while providing transparent supply chain information and documentation.
  • Emprove® Essential is for moderate-risk applications, offering compliance to IPEC-PQG GMP Guide and/or EXCiPACT™ Certification Standard, as well as supply chain transparency and regulatory support designed to assist drug manufacturers’ formalized risk assessments.
  • Emprove® Expert is for higher-risk applications where the lowest microbiological and endotoxin levels are of utmost importance. Along with the risk management features of Emprove® Essential, the Emprove® Expert line yields products with specified low microbiological and endotoxin levels, supporting the overall risk mitigation strategy.

Bulk Powder Transfer Bags for Safer, Faster Processing

To help you meet increasing industry demands for faster, more flexible bioprocessing, we can supply raw materials in pre-filled bulk powder transfer bags of 1–100 kg for operations of every scale. Bags are pre-weighed to within +/-0.5% accuracy, eliminating potential for error and connecting directly to your receiving vessel for mitigation of risks associated with contamination and employee safety. This service is one of many examples that set us apart as a partner committed to your process efficiency and quality, offering potential to eliminate labor-intensive steps such as rinsing, re-weighing, and cleanup from your buffer and media prep. 

Related Webinar

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An open laptop with a colorful display featuring a stylized human figure in blue on the right and a pink rectangle on the left against a yellow background.

Webinar: Identifying Appropriate-Quality Pharmaceutical Raw Materials in an Evolving Regulatory Environment

This webinar will discuss appropriate quality attributes for different raw material uses, present strategies to support identification, selection and risk assessment of raw materials, and highlight the importance of regulatory documentation.

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Related Product Categories
Bioprocessing Cell Culture Media
Our off-the-shelf and customizable bioprocessing cell culture media (CCM) products enhance productivity in upstream mAb, vaccine, gene/cell therapy processes.
Custom GMP Cell Culture Products
Our custom cell culture product design experts can offer advice and support as you scale your bioprocess from clinical to commercial supply, assisting with liquid products, dry powder products, selection of raw materials, quality testing, flexible product packaging, and product documentation.
Buffer & Media Prep
Explore our solutions for process solution buffer and media preparation, including our Mobius® single-use mixing and Mobius® FlexReady solutions.
Downstream Process & Formulation Chemicals
Our broad portfolio of downstream chemicals simplifies raw material specification with optimized quality attributes for all your applications – while providing industry-leading support and documentation to help navigate regulatory challenges, manage risks, and improve processes.
Related Services
Emprove® Program
Emprove® Program: The smart way to master compliance and control. Complementing our product portfolio, the Emprove® Program provides convenient access to reliable technical, regulatory and supply information in Emprove® Dossiers to support your risk assessment continuum.
Bulk Powder Transfer Bags
EZ BioPac® and Right Sized Weighing is a complete solution for easy and safe delivery of cell culture media and bioprocess chemicals. Our powder transfer system is designed to deliver exact weight of dry ingredients up to 100 kg and offers the right options for direct connection to your hydration vessels.
Emprove® Chemicals
To simplify raw material selection while satisfying regulatory requirements, our Emprove® Chemicals portfolio contains over 400 pharmaceutical raw materials offering the comprehensive, up-to-date documentation you need to navigate regulatory challenges, manage risks, and improve processes.
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