Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles.

Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles.

Chemical communications (Cambridge, England) (2012-03-14)

Lukas C Gerber, Nadine Moser, Norman A Luechinger, Wendelin J Stark, Robert N Grass

ABSTRACT

Lanthanum oxide nanoparticles were utilized to scavenge phosphate from microbial growth media for the use of targeted nutrient starvation as an antimicrobial strategy. Only in phosphate poor environments a toxic effect was observed. The effect was shown on Escherichia coli, Staphylococcus carnosus, Penicillium roqueforti, and Chlorella vulgaris.

MATERIALS

Product Number

Brand

Product Description

289205

Supelco

Lanthanum(III) oxide, suitable for AAS, ≥99.9%

203556

Sigma-Aldrich

Lanthanum(III) oxide, 99.999% trace metals basis

199923

Sigma-Aldrich

Lanthanum(III) oxide, 99.99% trace metals basis

L4000

Sigma-Aldrich

Lanthanum(III) oxide, ≥99.9%

634271

Sigma-Aldrich

Lanthanum(III) oxide, nanopowder, <100 nm particle size (TEM), 99% trace metals basis