Analysis of trifluoroacetic acid in lyophilized natural products by capillary electrophoresis.

A rapid and simple method for the capillary electrophoretic determination of residual trifluoroacetic acid in lyophilized natural products is described. The technique utilizes 2,6-naphthalenedicarboxylic acid as a separation buffer additive providing indirect ultraviolet absorption detection. Using this method, acceptable precision, accuracy, selectivity, range and linearity were achieved.