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  • Accelerated orthodontic tooth movement following le fort I osteotomy in a rodent model.

Accelerated orthodontic tooth movement following le fort I osteotomy in a rodent model.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (2014-03-19)
Hao Yuan, Xiaofang Zhu, Jingting Lu, Jiewen Dai, Bing Fang, Steve G F Shen
ABSTRACT

In surgery-first accelerated orthognathic surgery, the clinical phenomenon of accelerated orthodontic tooth movement after osteotomy is a benefit compared with the conventional approach. However, because much of the literature on this phenomenon is based on empirical evidence and case reports, experimental animal-based studies are needed to verify and quantify this acceleration effect. The purpose of this prospective experimental study was to identify whether osteotomy procedures increase tooth movement. Le Fort I osteotomies were performed on the left maxillas in 15 male adult Sprague-Dawley rats. After surgery, a continuous force of 0.5 N was placed on the maxillary left first molar to move the tooth mesially. Another 15 rats had no surgery and served as controls. On days 1, 14, and 28, digital caliper measurements were taken to record tooth movement. In the experimental group, the maxillary left first molars moved significantly more rapidly on days 14 and 28 (P < .05). Histologic findings showed more active alveolar bone remodeling. Le Fort I osteotomy significantly accelerated the rate of orthodontic tooth movement. Histologically, more active and extensive bone remodeling was observed after osteotomy.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Phosphatase, Acid from sweet potato, ammonium sulfate suspension, ≥10.0 units/mg protein (modified Warburg-Christian)
Sigma-Aldrich
Phosphatase, Acid from potato, lyophilized powder, ≥0.5 unit/mg solid
Sigma-Aldrich
Phosphatase, Acid from potato, lyophilized powder, ≥3.0 units/mg solid
Nickel, foil, 300x300mm, thickness 0.125mm, annealed, 99%
Nickel, foil, 0.5m coil, thickness 0.025mm, annealed, 99%
Nickel, foil, 50x50mm, thickness 1.0mm, as rolled, 99.999%
Nickel, foil, light tested, 50x50mm, thickness 0.05mm, 99.9%
Nickel, mesh, 30x30mm, nominal aperture 0.34mm, thickness 0.025mm, wire diameter 0.041mm, 70 wires/inch, open area 80%, electro-formed mesh, 99.9%
Nickel, foil, light tested, 300x300mm, thickness 0.03mm, 99.9%
Nickel, foil, 50x50mm, thickness 0.25mm, annealed, 99%
Nickel, foil, 25x25mm, thickness 0.5mm, as rolled, 99.99+%
Nickel, foil, 0.5m coil, thickness 0.075mm, as rolled, 99.98%
Nickel, wire reel, 10m, diameter 0.4mm, as drawn, 99%
Nickel, wire reel, 10m, diameter 0.25mm, annealed, 99%
Nickel, foil, 4mm disks, thickness 0.025mm, as rolled, 100%
Nickel, mesh, 130x130mm, nominal aperture 0.34mm, thickness 0.025mm, wire diameter 0.041mm, 70 wires/inch, open area 80%, electro-formed mesh, 99.9%
Nickel, foil, 0.5m coil, thickness 0.025mm, coil width 600mm, as rolled, 99%
Nickel, foil, 4mm disks, thickness 0.025mm, 99.9%
Nickel, wire reel, 0.5m, diameter 1.0mm, as drawn, 99.99+%
Nickel, foil, not light tested, 50x50mm, thickness 0.0025mm, 99.95%
Nickel, foil, 50x50mm, thickness 1.0mm, as rolled, 99.99+%
Nickel, foil, 50x50mm, thickness 0.125mm, as rolled, 99.999%
Nickel, foil, 25x25mm, thickness 0.25mm, as rolled, 99.999%
Nickel, foil, 0.5m coil, thickness 1.0mm, annealed, 99%
Nickel, rod, 100mm, diameter 10.0mm, 99.99+%
Nickel, pellets, 20g, max. size 10mm, 99.999%
Nickel, mesh, 65x65mm, nominal aperture 0.34mm, thickness 0.025mm, wire diameter 0.041mm, 70 wires/inch, open area 80%, electro-formed mesh, 99.9%
Nickel, foil, not light tested, 50x50mm, thickness 0.0125mm, 99.99+%
Nickel, foil, 25x25mm, thickness 2.0mm, annealed, 99%
Nickel, foil, 10mm disks, thickness 0.025mm, as rolled, 99.99+%