Skip to Content
Merck
All Photos(4)

Key Documents

View All Documentation

C7129

Sigma-Aldrich

Citric acid monohydrate

reagent grade, ≥98% (GC/titration)

Synonym(s):

2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2 · H2O
CAS Number:
5949-29-1
Molecular Weight:
210.14
Beilstein:
4018641
EC Number:
201-069-1
MDL number:
MFCD00149972
UNSPSC Code:
12352100
PubChem Substance ID:
24892935
NACRES:
NA.21

grade

reagent grade

Assay

≥98% (GC/titration)

form

powder

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

solubility

H2O: 100 mg/mL, clear, colorless (Turbidity)

SMILES string

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

InChI key

YASYEJJMZJALEJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Citric acid monohydrate(CAM) is an organic acid. It can be produced by crystallization from mother liquor of citric acid solution at 20-25°C during citric acid synthesis. Its molar enthalpy of solution in water has been reported to be ΔsolHm (298.15K, m = 0.0203molkg-1) = (29061±123)Jmol-1. An investigation of its crystal growth kinetics indicates that growth is linearly dependent on size.

Application

Citric acid monohydrate may be used:
  • To prepare citric acid solution employed in the acetone method of 68Ga pre-purification and radiolabeling technique.
  • To prepare Tris-citrate buffer employed for the electrophoresis of bacterial enzymes.
  • To improve the release of diltiazem hydrochloride from melt extruded matrix tablets.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

345.0 °F - closed cup

Flash Point(C)

173.9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000402243
0000402244
0000400234
0000400158
0000388455

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Size dependency of citric acid monohydrate growth kinetics.
Bravi M and Mazzarotta B.
Chemical Engineering Journal, 70(3), 203-207 (1998)
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics.
R K Selander et al.
Applied and environmental microbiology, 51(5), 873-884 (1986-05-01)
Michael K Schultz et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 76, 46-54 (2012-10-03)
A new NaCl based method for preparation of gallium-68 labeled radiopharmaceuticals has been adapted for use with an automated gallium-68 generator system. The method was evaluated based on 56 preparations of [(68)Ga]DOTATOC and compared to a similar acetone-based approach. Advantages
Sandra U Schilling et al.
International journal of pharmaceutics, 361(1-2), 158-168 (2008-06-28)
Incomplete drug release and particle size-dependent dissolution performance can compromise the quality of controlled release matrix systems. The objective of the current study was to investigate the ability of citric acid monohydrate (CA MH) to enhance the release of diltiazem
New perspectives for citric acid production and application.
Soccol CR, et al.
Food Technology and Biotechnology, 44(2), 141-149 (2006)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service