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  • Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: optimizing for cyclization-trapping over cycloisomerization.

Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: optimizing for cyclization-trapping over cycloisomerization.

Organic letters (2003-09-26)
James M Takacs, Scott D Schroeder, Jianxin Han, Meg Gifford, Xun-Tian Jiang, Twana Saleh, Suresh Vayalakkada, Amy H Yap
ABSTRACT

[reaction: see text] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
N-Hydroxyphthalimide, 97%