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O5879

Supelco

Ornidazole

analytical standard

Synonym(s):

1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole

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About This Item

Linear Formula:
C7H10N3O3Cl
CAS Number:
16773-42-5
Molecular Weight:
219.63
EC Number:
240-826-0
MDL number:
MFCD00057960
UNSPSC Code:
41116107
PubChem Substance ID:
329818917
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cc1ncc(n1CC(O)CCl)[N+]([O-])=O

InChI

1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3

InChI key

IPWKIXLWTCNBKN-UHFFFAOYSA-N

Application

Ornidazole has been used as a standard in the determination of traces of ornidazole in samples of aquaculture tissue using ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000395414
0000388136
0000388136
0000395414
0000272704

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Baljit Singh et al.
Colloids and surfaces. B, Biointerfaces, 82(2), 325-332 (2010-10-05)
In view of the antidiarrheal properties of sterculia gum and ornidazole, an attempt has been made to synthesize novel hydrogels by functionalization of sterculia gum with poly(vinylpyrrolidone) (PVP) for release of the model antidiarrheal drug ornidazole. These hydrogels were characterized
Fehmi Tabak et al.
Liver international : official journal of the International Association for the Study of the Liver, 23(5), 351-354 (2004-01-08)
Metronidazole and ornidazole, synthetic nitroimidazole derivatives, are used in the treatment of infections caused by anaerobic bacteria and protozoa. The drugs are well tolerated and serious side effects are very rarely encountered. Hepatotoxicity is a rare side effect and hitherto
Nathalie Mahé et al.
Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20)
The solid-state properties of antiprotozoal ternidazole (3-(2-methyl-5-nitroimidazol-1-yl)-propan-1-ol) have been studied. Crystals are triclinic in the temperature interval between 100 and 333 K (melting point) with two different molecular conformations present in the asymmetric unit (Z' = 2) and two of
Marta Dolores Mudry et al.
Mutation research, 721(1), 108-113 (2011-01-25)
The genotoxicity of two nitroimidazole derivatives, ornidazole (ONZ) and metronidazole (MTZ) in the peripheral blood lymphocytes of Cebus libidinosus (CLI) (Primates, Cebidae) was assessed. Endpoints measured included sister chromatid exchange (SCE) frequency, cell proliferation kinetics (CPK), replication index (RI), mitotic
Subhash S Vaghani et al.
Carbohydrate research, 347(1), 76-82 (2011-11-22)
In the present study, carboxymethyl chitosan was prepared from chitosan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole. Ornidazole was incorporated at the time of crosslinking of carboxymethyl chitosan. The
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