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A38401

Sigma-Aldrich

9-Aminoacridine hydrochloride monohydrate

98%

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About This Item

Empirical Formula (Hill Notation):
C13H10N2 · HCl · H2O
CAS Number:
52417-22-8
Molecular Weight:
248.71
Beilstein:
3707637
EC Number:
205-145-5
MDL number:
MFCD00150071
UNSPSC Code:
12352100
PubChem Substance ID:
24890818
NACRES:
NA.22

Quality Level

200

Assay

98%

form

powder

mp

300 °C (lit.)

λmax

400 nm
420 nm (2nd)

SMILES string

O.Cl.Nc1c2ccccc2nc3ccccc13

InChI

1S/C13H10N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1-8H,(H2,14,15);1H;1H2

InChI key

OREJEGKBQBIJSJ-UHFFFAOYSA-N

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Application

Mutagen.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nucleic acid-mutagen interactions: crystal structure of adenylyl-3',5'-uridine plus 9-aminoacridine.
N C Seeman et al.
Nature, 253(5490), 324-327 (1975-01-31)
Youn-Hwan Hwang et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 412736-412736 (2012-07-31)
Arisolochiae species plants containing aristolochic acids I and II (AA I and AA II) are well known to cause aristolochic acid nephropathy (AAN). Recently, there are various approaches to use AAs-containing herbs after the removal of their toxic factors. However
Na Sun et al.
Hypertension (Dallas, Tex. : 1979), 75(3), 634-644 (2020-01-21)
Aldosterone-producing adenomas (APAs) are one of the main causes of primary aldosteronism and the most prevalent surgically correctable form of hypertension. Aldosterone-producing cell clusters (APCCs) comprise tight nests of zona glomerulosa cells, strongly positive for CYP11B2 (aldosterone synthase) in immunohistochemistry.
Na Sun et al.
Endocrinology (2018-02-01)
In the adrenal gland, neuroendocrine cells that synthesize catecholamines and epithelial cells that produce steroid hormones are united beneath a common organ capsule to function as a single stress-responsive organ. The functional anatomy of the steroid hormone producing adrenal cortex
Masanori Murakami et al.
JCI insight, 4(17) (2019-09-06)
Recent genetic examinations and multisteroid profiles have provided the basis for subclassification of aldosterone-producing adenomas (APAs). The objective of the current study was to produce a comprehensive, high-resolution mass spectrometry imaging (MSI) map of APAs in relation to morphometry, immunohistochemical
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