8.05958

Manganese(IV) oxide

(precipitated active) for synthesis

• Synonym(s): Manganese(IV) oxide, Manganese dioxide, Pyrolusite
• Empirical Formula (Hill Notation): MnO₂
• CAS Number: 1313-13-9
• Molecular Weight: 86.94
• MDL number: MFCD00003463
• UNSPSC Code: 12352303
• EC Index Number: 215-202-6
• NACRES: NA.22

Properties

• Quality Level: 200
• form: powder
• potency: >3478 mg/kg LD₅₀, oral (Rat)
• reaction suitability: reagent type: oxidant
• solubility: insoluble <0.001 g/L
• density: 5.21 g/cm³ at 21 °C
• bulk density: 600‑800 kg/m³
• storage temp.: 2-30°C
• InChI: 1S/Mn.2O
• InChI key: NUJOXMJBOLGQSY-UHFFFAOYSA-N

Description

Application

Manganese(IV) oxide (MnO₂) can be used as an oxidizing agent for the oxidation of:

• Allylic alcohols to α, β-ethylenic aldehydes, or ketones.
• Propargylic alcohols to alkynic aldehydes or ketones.
• Benzylic and heterocyclic alcohols to conjugated aromatic aldehydes or ketones.
• Amines to aldehydes, imines, amides, and diazo compounds. Methyl arenes to form primary amides in the presence of urea and oxygen.
• MnO₂ can also be used to synthesize disubstituted oxazolines from aldoximes via in situ nitrile oxide formation. Non-activated cyclic and acyclic alcohols oxidized to ketone analogs using stoichiometric MnO₂ and a ruthenium catalyst.

Analysis Note

Assay (iodometric, calc. on dried substance): ≥ 90.0 %
Loss on drying: ≤ 3.5 %
Oxidation Activity: passes test

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 + H332 - H373
• Precautionary Statements: P260 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 Inhalation
• Target Organs: Brain
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): does not flash
• Flash Point(C): does not flash