14379

MS calibration solution

API; sodium iodide (2 μg/μL) and cesium iodide (50 ng/μL) in 50/50 2-propanol/water

• Synonym(s): Mass spectrometry calibration standard
• UNSPSC Code: 12000000
• NACRES: NA.21

Properties

• Quality Level: 100
• form: liquid
• density: 0.910-0.950 g/mL at 20 °C
• suitability: in accordance for LC-MS
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care

Description

Application

• Therapeutic drug monitoring in oncology: MS calibration solutions are crucial in the development and validation of ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) methods for the quantitation of pralsetinib in human plasma and cerebrospinal fluid, enhancing therapeutic drug monitoring in oncology (Zhao et al., 2024).


• Continuous homogenous liquid phase microextraction: In the analysis of aliphatic amines in urine, a new microextraction technique utilizing MS calibration solutions based on in-situ preparation of deep eutectic solvent demonstrates advancements in gas chromatography-mass spectrometry (GC-MS) applications (Shagaghipour et al., 2024).


• Detection of toxic substances in pharmaceuticals: MS calibration solutions aid in the selective quantitation of ethylene and diethylene glycol in pediatric syrups using gas chromatography-tandem mass spectrometry, ensuring product safety and compliance with pharmaceutical standards (Altamimy et al., 2024).


• Bioequivalence studies: The application of MS calibration solutions in LC-MS/MS methods facilitates the rapid detection and validation of vonoprazan fumarate in human plasma, critical for conducting bioequivalence studies in clinical pharmacology (Chen et al., 2024).


• Electrochemical detection of heavy metals: MS calibration solutions are utilized in modifying carbon-fiber microelectrodes with gold nanoparticles for the electrochemical detection of cadmium via fast-scan cyclic voltammetry, highlighting their utility in environmental monitoring and public health safety (Manring et al., 2024).

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H336
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 71.6 °F
• Flash Point(C): 22 °C