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Tuneable nanochannel formation for sample-in/answer-out devices.

Chemical communications (Cambridge, England) (2013-02-28)
Aliaa I Shallan, Adam J Gaudry, Rosanne M Guijt, Michael C Breadmore
ABSTRACT

Control of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Rhodamine 6G, suitable for fluorescence, BioReagent
Sigma-Aldrich
Rhodamine 6G, Dye content 99 %
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Rhodamine 6G, Dye content ~95 %
Supelco
Rhodamine 6G, analytical standard