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534064

Sigma-Aldrich

Acetone

histological grade, ≥99.5%

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About This Item

Linear Formula:
CH3COCH3
CAS Number:
Molecular Weight:
58.08
Beilstein:
635680
EC Number:
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:
NACRES:
NA.21

grade

histological grade

Quality Level

vapor density

2 (vs air)

vapor pressure

184 mmHg ( 20 °C)

Assay

≥99.5%

form

liquid

expl. lim.

13.2 %

impurities

<0.5% water

evapn. residue

<0.001%

refractive index

n20/D 1.359 (lit.)

pH

5-6 (20 °C, 395 g/L)

bp

56 °C/760 mmHg (lit.)

mp

−94 °C (lit.)

solubility

water: miscible

density

0.791 g/mL at 25 °C (lit.)

application(s)

histology

format

neat

SMILES string

CC(C)=O

InChI

1S/C3H6O/c1-3(2)4/h1-2H3

InChI key

CSCPPACGZOOCGX-UHFFFAOYSA-N

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General description

Acetone is an organic solvent widely used in the polymer and pharmaceutical industry. It is found in mammalian tissues as a by-product of metalbolism. It shows potent anticonvulsant property. Acetone in combination with tetraalkylammonium chloride forms an efficient solvent system for dissolving cellulose. The dehydration of acetone can be accomplised by pervaporation using P84 (polyimide membrane)/TAEA (tripodal amine (tris(2-aminoethyl)amine) cross-linked asymmetric flat sheet membranes. The acetone vapors can undergo photolysis in a titanium dioxide (TiO2) photocatalyst immobilized UV irradiated reactor.

Application

Acetone may be employed in the following studies:
  • As a precursor for the synthesis of methyl isobutyl ketone (MIBK) in the presence of sulfonated graphene oxide-Pd/cordierite catalyst.
  • Synthesis of (4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane), a solketal from glycerol using supercritical fluids (SCF) technology.
  • As a starting material to synthesize methyl methacrylate.
It may be used in the synthesis of the following acetone hydrazones:
  • 1-isopropylidene-2-methylhydrazine
  • 1-isopropylidene-2-hydroxyethylhydrazine
  • 1-isopropylidene-2-formylhydrazine
Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17.0 °C - closed cup


Certificates of Analysis (COA)

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Johanson G.
Patty's Industrial Hygiene and Toxicology, 735-752 (2012)
Acetone as an anticonvulsant.
Likhodii S, et al.
Epilepsia, 49(8), 83-86 (2008)
Marc Kostag et al.
Macromolecular rapid communications, 35(16), 1419-1422 (2014-06-14)
Acetone containing tetraalkylammonium chloride is found to be an efficient solvent for cellulose. The addition of an amount of 10 mol% (based on acetone) of well-soluble salt triethyloctylammonium chloride (Et3 OctN Cl) adjusts the solvent's properties (increases the polarity) to
Sulfonated graphene oxide supported Pd bifunctional catalyst for one-pot synthesis of methyl isobutyl ketone from acetone with high conversion and selectivity.
Liu M, et al.
J. Mol. Catal. A: Chem., 408, 85-90 (2015)
Photocatalytic degradation of acetone and methanol in a flow-through photoreactor with immobilized TiO2.
Moulis F and Krysa J.
Research on Chemical Intermediates, 41(12), 9233-9242 (2015)

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