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Key Documents

G6514

Sigma-Aldrich

Gelatin veronal buffer

Synonym(s):

GVB2+, Gelatin Barbital Buffer

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About This Item

UNSPSC Code:
12161700
NACRES:
NA.25

form

liquid

Quality Level

200

drug control

Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

pH

7.3-7.4

storage temp.

2-8°C

Other Notes

0.15 mM CaCl2, 141 mM NaCl, 0.5 mM MgCl2, 0.1% gelatin, 1.8 mM sodium barbital and 3.1 mM barbituric acid, pH 7.3-7.4.
Aseptically filtered

Preparation Note

Below 35-40 °C, gelatin swells in and absorbs 5-10 times its weight of water to form a gel. Gelatin is more soluble in hot than in cold water. If visible floaters or cloudiness is evident, solution may be warmed in 45°C water bath for 10 minutes to achieve clear, colorless solution.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000387193
0000385843
0000375386
0000367143
0000370973

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Daniela M Ferreira et al.
Clinical and vaccine immunology : CVI, 15(3), 499-505 (2008-01-11)
We have previously shown that DNA immunization with PspA (pneumococcal surface protein A) DNA is able to elicit protection comparable to that elicited by immunization with PspA protein (with alum as adjuvant), even though the antibody levels elicited by DNA
Meghan A Morrissey et al.
Immunity, 53(2), 290-302 (2020-08-10)
CD47 acts as a "don't eat me" signal that protects cells from phagocytosis by binding and activating its receptor SIPRA on macrophages. CD47 suppresses multiple different pro-engulfment "eat me" signals, including immunoglobulin G (IgG), complement, and calreticulin, on distinct target
Nancy K Nyakoe et al.
Malaria journal, 8, 7-7 (2009-01-13)
Complement (C) can be activated during malaria, C components consumed and inflammatory mediators produced. This has potential to impair host innate defence. In a case-control study, C activation was assessed by measuring serum haemolytic activity (CH50), functional activity of each

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