Skip to Content
Merck
All Photos(1)

Key Documents

CF0036

Sigma-Aldrich

Trifluoromethyl azide

0.5 M in THF

Synonym(s):

Azidotrifluoromethane

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
CF3N3
CAS Number:
3802-95-7
Molecular Weight:
111.03
UNSPSC Code:
12352125
NACRES:
NA.06

Quality Level

100

concentration

0.5 M in THF

SMILES string

FC(N=[N+]=[N-])(F)F

InChI

1S/CF3N3/c2-1(3,4)6-7-5

InChI key

VTWUWWKZOBMMPO-UHFFFAOYSA-N

General description

Trifluoromethyl azide is a fluoroalkyl azide reagent active in copper-catalyzed azide-alkyne cycloaddition (click reaction). The usage of this and other perfluoroalkyl reagents in this family allows for the previously challenging inclusion of fluorinated species as building blocks for click reactions.

Learn more about fluorinated click chemistry

Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

-6.2 °F

Flash Point(C)

-21.2 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Fluorinated Azides: Click Chemistry Meets Fluorine

Fluorinated azides are a new tool that can be used to introduce fluorinated groups to molecules. These molecules can utilize click chemistry to easily add fluorinated groups.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service