Characterization of 1,2-benzo-8-(2-aminoethyl)-3-phenoxazone.

The compound 1,2-benzo-8-(2-aminoethyl)-3-phenoxazone (1) is synthesized by reacting tyramine with 1-nitroso-2-naphthol in the presence of nitric acid. During the reaction, tyramine and 1-nitroso-2-naphthol undergo condensation, ring closure, and subsequent oxidation steps to form 1. Compound 1 is characterized by one- and two-dimensional NMR spectroscopy and mass spectrometry. The proposed mechanism of reaction is based on the spectroscopic data. This reaction can be applied as a spot test analysis for analogous phenolic compounds.