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Merck
모든 사진(1)

Key Documents

100625

Sigma-Aldrich

3-Amino-1,2,4-triazine

97%

동의어(들):

3-Amino-as-triazine, [1,2,4]Triazin-3-ylamine

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About This Item

실험식(Hill 표기법):
C3H4N4
CAS Number:
Molecular Weight:
96.09
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

분석

97%

mp

174-177 °C (lit.)

SMILES string

Nc1nccnn1

InChI

1S/C3H4N4/c4-3-5-1-2-6-7-3/h1-2H,(H2,4,5,7)

InChI key

MJIWQHRXSLOUJN-UHFFFAOYSA-N

일반 설명

3-amino-1,2,4-triazine (ATN) acts as a single molecular carbon nitride precursor during the preparation of mesoporous carbon nitride with high nitrogen content via polymerization. Additionally, it is also used in the synthesis of organometal complexes.

애플리케이션

  • Antitumor activity in pharmaceutical applications: A study reported the development of a new library of 3-Amino-1,2,4-Triazine derivatives as PDK1 inhibitors, showing significant antitumor activity against pancreatic ductal adenocarcinoma, indicating its potential in cancer therapeutics (Carbone et al., 2023).
  • Structural analysis in crystallography: The crystal structure and Hirshfeld surface analysis of a complex involving 3-Amino-1,2,4-triazine was detailed, providing insights into the molecular interactions and potential applications in materials science and coordination chemistry (Sangeetha et al., 2018).
  • Catalytic applications in NMR technology: 3-Amino-1,2,4-triazine was used in a study to achieve significant NMR polarization in water using the SABRE technique, demonstrating its role as a catalyst in enhancing NMR sensitivity and its utility in magnetic resonance imaging (Zeng et al., 2014).

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

P A Taheri et al.
The Journal of clinical investigation, 93(1), 147-154 (1994-01-01)
Ultrasonic probes were placed around dog femoral arteries to record blood flow. Hind paw scalding with boiling water (5 s) caused a marked increase in ipsilateral femoral blood flow that persisted for the 2-h observation period. Contralateral femoral blood flow
Crystal structure of 3-amino-1,2,4-triazin-5(2H)-one.
Long-Chih Hwang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(6), 723-724 (2002-06-27)
S S Greenberg et al.
Life sciences, 57(21), 1949-1961 (1995-01-01)
We evaluated the effect of in vivo and in vitro administration of nitro-containing and nitro-deficient L-arginine-derived nitric oxide (NO) synthase inhibitors on the measurement of NO in plasma, urine and HEPES buffered physiologic salt solution (PSS) by ozone chemiluminescence and
Jirí Hanusek et al.
Organic & biomolecular chemistry, 5(3), 478-484 (2007-01-26)
Contrary to a previous report, the sulfurisation of phosphorus(III) derivatives by 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride) does not yield carbon disulfide and cyanamide as the additional reaction products. The reaction of xanthane hydride with triphenyl phosphine or trimethyl phosphite yields triphenyl phosphine
Copper (II) complexes of 3-amino-1, 2, 4-triazine and 2-aminopyrazine: Strategies for designing crystalline materials using coordination polymers
Li L, et al.
Inorganica chimica acta, 362, 3845-3852 (2009)

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