모든 사진(1)
About This Item
실험식(Hill 표기법):
C5H12N2
CAS Number:
Molecular Weight:
100.16
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22
추천 제품
분석
97%
형태
liquid
광학 활성
[α]20/D +20°, c = 1 in chloroform
refractive index
n20/D 1.482 (lit.)
bp
65 °C/11 mmHg (lit.)
density
0.933 g/mL at 25 °C (lit.)
SMILES string
NC[C@@H]1CCCN1
InChI
1S/C5H12N2/c6-4-5-2-1-3-7-5/h5,7H,1-4,6H2/t5-/m0/s1
InChI key
AUKXFNABVHIUAC-YFKPBYRVSA-N
일반 설명
(S)-(+)-2-(Aminomethyl)pyrrolidine is a chiral vicinal diamine.
애플리케이션
(S)-(+)-2-(Aminomethyl)pyrrolidine can be used as an organocatalyst:
It can also be used as a reactant to prepare Schiff base metal complexes with pyrrolidine fragment as a ligand in asymmetric synthesis.
- For the asymmetric transformation of (S)-alanine.
- In the asymmetric α-fluorination of linear and branched aldehydes using N-fluorobenzenesulfonamide as the fluorinating agent.
It can also be used as a reactant to prepare Schiff base metal complexes with pyrrolidine fragment as a ligand in asymmetric synthesis.
Used in the synthesis of compounds with antitumor activity.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
116.6 °F - closed cup
Flash Point (°C)
47 °C - closed cup
개인 보호 장비
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
K Morikawa et al.
Journal of pharmaceutical sciences, 80(9), 837-842 (1991-09-01)
The optical isomers of 2-aminomethylpyrrolidine(1,1-cyclobutane- dicarboxylato)platinum(II) (DWA2114, 1), which has potent antitumor activity against various tumors, were synthesized. They were examined for antitumor activity against Colon 26 carcinoma in a sc-iv system, and changes in urinary protein and sugar levels
Dioxovanadium (V) complexes of Schiff bases derived from S-(+)-2-(aminomethyl) pyrrolidine and aromatic o-hydroxycarbonyl compounds: Synthesis, characterization and structure
Kwiatkowski E, et al.
Polyhedron, 25(15), 2809-2814 (2006)
Direct asymmetric α-fluorination of aldehydes
Steiner DD, et al.
Angewandte Chemie (International ed. in English), 44(24), 3706-3710 (2005)
Asymmetric Transformation of Alanine via Optically Labile Imidazolines
Shibata S, et al.
Bulletin of the Chemical Society of Japan, 52(10), 2938-2941 (1979)
문서
Chiral vicinal diamines are of tremendous interest to the synthetic chemist as they are found in many chiral catalysts and pharmaceuticals.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.