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Merck
모든 사진(1)

Key Documents

935441

Sigma-Aldrich

Aldehyde functionalized hyaluronic acid

Degree of functionalization ~20%

동의어(들):

HA-A, Hyaluronic acid, Hyluronic acid aldehyde, Oxidized hyaluronic acid

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About This Item

Linear Formula:
(C14H20NNaO11)n(C14H18NNaO11)m
UNSPSC 코드:
12352201
NACRES:
NA.28

Quality Level

형태

powder or chunks (or fibers)

색상

white to off-white

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Hyaluronic acid (HA) is an important component of the natural extracellular matrix which plays a vital role in various cellular and tissue functions. It represents some unique properties such as excellent gel-forming properties and chemical modification ability through hydroxyl and carboxyl groups that make them potentially useful for their application in Tissue engineering. Partially oxidized hyaluronate (OHA) containing two highly aldehyde groups in the repeating unit of HA. The dialdehyde groups of OHA are capable of reductive coupling with primary amines and thus can be used in a wide range of chemical modifications of HA as hydrogel for tissue engineering applications and regenerative medicine drug delivery applications

애플리케이션

HA is increasingly used for a many biomedical applications because it promotes cell migration, angiogenesis, cell viability, and proliferation. Aldehyde functionalized HA can be used to develop hydrogels for tissue engineering, regenerative medicing, bioprinting, and drug delivery applications.

특징 및 장점

  • Coupling capabilities with primary amines
  • Biocompatible functionalized natural polymer
  • Promotes a variety of cellular and tissue functions

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Strategies for Hyaluronic Acid-Based Hydrogel Design in Drug Delivery
Sonia T, et al.
Pharmaceutics, 11, 407-407 (2019)
Oxi-HA/ADH Hydrogels: A Novel Approach in Tissue Engineering and Regenerative Medicine
Franca G C, et al.
Polysaccharides, 2, 477-496 (2021)
Hyaluronic Acid and Controlled Release: A Review
Bayer S I, et al.
Molecules (Basel), 25, 2649-2649 (2020)
General Dialdehyde Click Chemistry for Amine Bioconjugation
Elahipanah S, et al.
Bioconjugate Chemistry, 28, 1422-1433 (2017)
Modified hyaluronic acid-based materials for biomedical applications
Tiwari S, et al.
International Journal of Biological Macromolecules, 121, 556-571 (2019)

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