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Merck
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Key Documents

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M1626

Sigma-Aldrich

6-Methoxyharmalan

crystalline

동의어(들):

4,9-Dihydro-6-methoxy-1-methyl-3H-pyrido(3,4-b)indole

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C13H14N2O
CAS Number:
3589-73-9
Molecular Weight:
214.26
MDL number:
MFCD00055938
UNSPSC 코드:
12352100
PubChem Substance ID:
57654356
NACRES:
NA.22

형태

crystalline

색상

yellow

저장 온도

2-8°C

SMILES string

COc1ccc2[nH]c3C(C)=NCCc3c2c1

InChI

1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3

InChI key

HMBHRMFLDKKSCT-UHFFFAOYSA-N

유전자 정보

human ... CHRM1(1128) , CHRM2(1129) , CHRM4(1132) , CHRM5(1133) , DRD1(1812) , DRD5(1816) , HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR2C(3358) , HTR3A(3359) , HTR5A(3361) , HTR6(3362) , HTR7(3363) , LOC730413(730413) , SLC6A2(6530) , SLC6A4(6532)
rat ... Drd2(24318) , Drd3(29238) , Drd4(25432) , Htr2a(29595)

애플리케이션

  • Reactant for preparation of TRPV1-dependent vasodilator

생화학적/생리학적 작용

Weak serotonin inhibitor

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

V P Poshivalov
Biulleten' eksperimental'noi biologii i meditsiny, 99(3), 323-325 (1985-03-01)
The ethological spectrum of four beta-carbolines was studied for intraspecific aggression, sociability integration and individual behavior. It was established that beta-carboline-3-carboxyethyl ether given at subconvulsant doses increases aggression, lowers sociability as a diazepam antagonist. Diazepam reduces aggression and increases sociability.
Fernando D Villarruel et al.
Physical chemistry chemical physics : PCCP, 22(36), 20901-20913 (2020-09-12)
3,4-Dihydro-β-carbolines (DHβCs) are a set of endogenously synthesized alkaloids spread over a great variety of living species (e.g., plants, animals and microorganisms), playing a broad spectrum of biological, biochemical and/or pharmacological roles, in a structure-dependent manner. Addressing unresolved fundamental aspects
Sudeep Karki et al.
Analytical biochemistry, 587, 113463-113463 (2019-10-02)
Synaptic adhesion molecules, including presynaptic neurexins (NRXNs) and post-synaptic leucine-rich repeat transmembrane (LRRTM) proteins are important for development and maintenance of brain neuronal networks. NRXNs are probably the best characterized synaptic adhesion molecules, and one of the major presynaptic organizer
M Micaela Gonzalez et al.
International journal of antimicrobial agents, 52(4), 459-468 (2018-07-15)
Several commercial and novel synthetic β-carbolines (βCs) were evaluated for their antiviral activity against herpes simplex virus type 1 (HSV-1) using an adapted MTS assay. Of 21 drugs tested, although 11 exerted antiviral activity at non-cytotoxic concentrations, only 3 of

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