LM1304
Avanti
17:0-14:1 PS
Avanti Research™ - A Croda Brand LM1304, methanol solution
동의어(들):
1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine (ammonium salt)
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C37H73N2O10P
CAS Number:
Molecular Weight:
736.96
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
형태
methanol solution
포장
pkg of 1 × 1 mL (LM1304-1EA)
제조업체/상표
Avanti Research™ - A Croda Brand LM1304
농도
~10 μg/mL (Refer to C of A for lot specific concentration. )
응용 분야
lipidomics
metabolomics
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]
일반 설명
Phosphatidylserine (PS) is an acidic phospholipid present in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues.
애플리케이션
17:0-14:1 PS or 1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine has been used as an internal standard:
- for the detection of lipids by tandem mass spectrometry (MS/MS)
- to determine lipid concentration in human primary myotubes lipid extracts by mass spectrometry (MS) analysis
- for phospholipid quantification by MS
- for lipid extraction by methyl tert-butyl ether (MTBE) method
- for lipid quantification using liquid chromatography (LC)-MS
생화학적/생리학적 작용
Phosphatidylserine (PS) is associated with the Akt, protein kinase C (PKC) and Raf-1 signaling. It supports neuronal survival, neurite growth and synaptogenesis.
포장
2 mL Amber Glass Sealed Ampule (LM1304-1EA)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
제품 번호
설명
가격
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
표적 기관
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point (°F)
49.5 °F - closed cup
Flash Point (°C)
9.7 °C - closed cup
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Hee-Yong Kim et al.
Progress in lipid research, 56, 1-18 (2014-07-06)
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in neural tissues. PS is synthesized from phosphatidylcholine or phosphatidylethanolamine by exchanging the base head group with serine, and this reaction is
Laurent Perrin et al.
eLife, 7 (2018-04-17)
Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsies in vivo with profiles of human skeletal myotubes synchronized in vitro. More extensive
Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Yakir Guri et al.
Cancer cell, 32(6), 807-823 (2017-12-13)
Dysregulated mammalian target of rapamycin (mTOR) promotes cancer, but underlying mechanisms are poorly understood. We describe an mTOR-driven mouse model that displays hepatosteatosis progressing to hepatocellular carcinoma (HCC). Longitudinal proteomic, lipidomics, and metabolomic analyses revealed that hepatic mTORC2 promotes de
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