210150

Cantharidic Acid

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

• 동의어(들): Cantharidic Acid, 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy- endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
• 실험식(Hill 표기법): C₁₀H₁₄O₅
• CAS Number: 28874-45-5
• Molecular Weight: 214.22
• MDL number: MFCD00047137
• UNSPSC 코드: 12352106
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: >95% (TLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: warm ethanol: 10 mg/mL; DMSO: 25 mg/mL
• 배송 상태: ambient
• 저장 온도: 10-30°C
• InChI: 1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)/t5-,6+,9-,10+
• InChI key: NMTNUQBORQILRK-YUMGAWCOSA-N

설명

일반 설명

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

Inhibits protein phosphatase 2A (IC₅₀ = 50 nM).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
PP2A

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 50 nM against protein phosphatase 2A

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Zhang, Z., et al. 1996. Biochemistry35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol.33, 706.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3