475989
MTT
Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan.
동의어(들):
MTT, 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium Bromide, Thiazole Blue
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H16BrN5S
CAS Number:
Molecular Weight:
414.32
MDL number:
UNSPSC 코드:
12171500
NACRES:
NA.25
추천 제품
Quality Level
분석
≥98% (silver nitrate titration)
형태
solid
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
불순물
≤0.5% Sulfated ash
색상
yellow
solubility
PBS: 2 mg/mL
양이온 미량물
heavy metals: ≤0.001%
배송 상태
ambient
저장 온도
15-25°C
InChI
1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI key
AZKSAVLVSZKNRD-UHFFFAOYSA-M
일반 설명
Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.
생화학적/생리학적 작용
Cell permeable: yes
Primary Target
Used as a direct indicator of cytotoxicity and apoptosis.
Used as a direct indicator of cytotoxicity and apoptosis.
Product does not compete with ATP.
Reversible: no
경고
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
재구성
Following reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.
기타 정보
Liu, Y., et al. 1997. J. Neurochem.69, 581.
Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Yi Shan Huang et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 7202519-7202519 (2020-05-19)
Hypertensive renal injury is a primary etiology of end-stage renal disease, and satisfactory therapeutic strategies are urgently required. Cordyceps cicadae, a traditional Chinese herb, has potential renoprotective benefits and is widely used in the treatment of many kidney diseases. To
Jong-Chan Park et al.
Nature communications, 12(1), 280-280 (2021-01-14)
Developing effective drugs for Alzheimer's disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD with
Ning Wang et al.
Journal of inorganic and organometallic polymers and materials, 1-15 (2020-05-13)
Vulnerability of respiratory mucosa to invasions of airborne pathogens, such as SARS-CoV, MERS-CoV and avian viruses which sometimes cause a life-threatening epidemic and even pandemic, underscores significance of developing a pulmonary vaccine adjuvant-delivery system (VADS). Herein, 30-nm aluminum nanoparticles (ANs)
Matshediso Zachariah et al.
Journal of cellular physiology, 236(6), 4348-4359 (2020-11-27)
Selenium is an essential trace element important for human health. A balanced intake is, however, crucial to maximize the health benefits of selenium. At physiological concentrations, selenium mediates antioxidant, anti-inflammatory, and pro-survival actions. However, supra-nutritional selenium intake was associated with
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.