8.22339

Phosphoryl chloride

for synthesis

• 동의어(들): Phosphoryl chloride, Phosphorus oxide trichloride, Phosphorus oxychloride
• CAS Number: 10025-87-3
• Molecular Weight: 153.33
• MDL number: MFCD00011443
• UNSPSC 코드: 12352101
• EC 인덱스 번호: 233-046-7
• NACRES: NA.22

속성

• vapor pressure: 36 hPa ( 20 °C)
• Quality Level: 200
• 분석: ≥99.0% (argenometric)
• 형태: liquid
• 효능: 36 mg/kg LD₅₀, oral (Rat)
• pH: 1.0 (25 °C, 5 g/L in H₂O)
• bp: 105.3 °C/1013 hPa
• mp: 1-2 °C
• density: 1.68 g/cm³ at 20 °C (DIN 51757)
• 저장 온도: 2-30°C
• InChI: 1S/Cl3OP/c1-5(2,3)4
• InChI key: XHXFXVLFKHQFAL-UHFFFAOYSA-N

설명

일반 설명

for synthesis

애플리케이션

Phosphoryl chloride is a strong Lewis acid that can be used as:

• A phosphorylating agent for the selective phosphorylation of alcohols, amines, and thiols.
• A dehydrating agent for alcohols, amides, and cyanohydrins.
• A reagent to synthesize Vilsmeier reagent for Vilsmeier-Haack formylation reactions.
• A chlorinating agent for the chlorination of heterocyclic compounds.
• A reagent to prepare dihydroisoquinolines and isoquinolines by cyclization of N-β-phenylethyl amides via Bischler-Napieralski reaction.

분석 메모

Assay (argentometric)≥ 99.0 %Density (d 20 °C/ 4 °C)1.673 - 1.677Identity (IR)passes test

안전성 정보

• 픽토그램: GHS05,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302 - H314 - H330 - H372
• 예방조치 성명서: P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1 - STOT RE 1 Inhalation
• 표적 기관: Respiratory Tract
• 보충제 위험성: EUH014 - EUH029
• Storage Class Code: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable