MAB4419A4
Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor™ 488 conjugate
clone 7F9.2, from mouse, ALEXA FLUOR™ 488
동의어(들):
POU domain class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3
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모든 사진(2)
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About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
추천 제품
![Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2 clone 7F9.2, from mouse](/deepweb/assets/sigmaaldrich/product/images/307/874/7354f72d-80ee-40a5-b7fa-0590fe6784cc/640/7354f72d-80ee-40a5-b7fa-0590fe6784cc.jpg)
일반 설명
Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis, expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been identified as one of the main transcription factors required to reprogram somatic cells into induced pluripotent stem cells (iPS cells).
애플리케이션
Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor 488 conjugate is an antibody against OCT-4 [POU5F1] for use in ICC.
품질
Evaluated by Immunocytochemistry in mouse embryonic stem cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Oct-4 in mouse embryonic stem cells (SCR012).
표적 설명
The uncojugated parent antibody (Catalog No. MAB4419) has an observed MW at 39 kDa
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
ALEXA FLUOR is a trademark of Life Technologies
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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PloS one, 15(6), e0234262-e0234262 (2020-06-10)
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Oncotarget, 8(5), 7814-7826 (2016-12-22)
Primordial germ cells (PGCs) derived from human embryonic stem cells (hESCs) represent as a desirable experimental model as well as a potential strategy for treating male infertility. Here, we developed a simple and feasible method for differentiation of PGCs from
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Cell research (2021-06-24)
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International journal of molecular medicine, 35(3), 569-578 (2014-12-20)
The present study aimed to investigate the X chromosome inactivation (XCI) status in long-term cultured human parthenogenetic embryonic stem cells. One human embryonic stem (hES) cell line and 2 human parthenogenetic embryonic stem (hPES) cell lines were subjected to long-term
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