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Merck
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문서

PHR1687

Supelco

Cyclohexane

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Cyclohexane

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About This Item

실험식(Hill 표기법):
C6H12
CAS Number:
Molecular Weight:
84.16
Beilstein:
1900225
EC Number:
MDL number:
UNSPSC 코드:
12191502
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1601408

vapor density

2.9 (vs air)

vapor pressure

168.8 mmHg ( 37.7 °C)
77 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

500 °F

expl. lim.

9 %

포장

ampule of 3x1.2 mL

기술

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.426 (lit.)

bp

80.7 °C (lit.)

mp

4-7 °C (lit.)

density

0.779 g/mL at 25 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

C1CCCCC1

InChI

1S/C6H12/c1-2-4-6-5-3-1/h1-6H2

InChI key

XDTMQSROBMDMFD-UHFFFAOYSA-N

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일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Cyclohexane is a nonpolar, flammable liquid that belongs to the group of cycloalkanes. In general, cyclohexane is obtained by hydrogenation of benzene and predominately used in the nylon industry. It also finds application in pharmaceutical applications.

애플리케이션

Cyclohexane can be used as a pharmaceutical reference standard for residual solvent analysis in pharmaceutical formulations and raw materials by gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC0291 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

-4.0 °F - closed cup

Flash Point (°C)

-20 °C - closed cup


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이미 열람한 고객

Slide 1 of 2

1 of 2

Residual solvents determination in drug products by static headspace-gas chromatography
Camarasu CC
Chromatographia, 56(1), S137-S143 (2002)
Validation of a generic analytical procedure for determination of residual solvents in drug substances
Klick S and Skold A
Journal of Pharmaceutical and Biomedical Analysis, 36(2), 401-409 (2004)
Pervaporation: Membrane Separations
Encyclopedia of Separation Science, 3636-3641 (2000)
Organic solvents in the pharmaceutical industry
Grodowska K and Parczewski A
Acta Poloniae Pharmaceutica, 67(1), 3-12 (2010)

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