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Merck
모든 사진(1)

Key Documents

363M-1

Sigma-Aldrich

PAX-8 (MRQ-50) Mouse Monoclonal Antibody

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

MRQ-50, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (363M-14)
vial of 0.5 mL concentrate (363M-15)
bottle of 1.0 mL predilute (363M-17)
vial of 1.0 mL concentrate (363M-16)
bottle of 7.0 mL predilute (363M-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry: 1:50-1:200

동형

IgG

배송 상태

wet ice

저장 온도

2-8°C

유전자 정보

human ... PAX8(7849)

일반 설명

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidneys, and thyroid, with continued expression in some epithelial cell types of these mature tissues.PAX-8 is a useful marker for neoplasms of gynecologic renal and thyroidorigin.PAX-8 (MRQ-50) antibody targets the N-terminus of the PAX-8 molecule. This section of the protein is shared with other PAX proteins such as PAX-5 and PAX-6; thus, some cross-reactivity with these proteins may be observed as evidenced by the labeling of selected lymphocytes, and neuroendocrine cells.

품질


IVD

IVD

IVD

RUO

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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문서 라이브러리 방문

Inigo Espinosa et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 34(3), 257-265 (2015-04-07)
Breast carcinomas rarely metastasize to the ovary and are even more rarely present clinically as primary ovarian tumors. However, patients with breast cancer not infrequently develop independent primary ovarian carcinomas. In these cases, distinction between independent primaries and metastatic tumors
Meaghan L Barr et al.
Journal of clinical pathology, 68(1), 12-17 (2014-10-16)
Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs. Two distinct tissue microarrays
Mark J Mentrikoski et al.
Applied immunohistochemistry & molecular morphology : AIMM, 22(9), 635-641 (2014-10-04)
Clear-cell renal cell carcinoma (CC-RCC) is the most common primary kidney malignancy, yet this morphology is not unique to renal primary tumors, as clear-cell variants of numerous nonrenal carcinomas of varying lineages exist. Therefore, because of CC-RCC's ability to metastasize
Nelson G Ordóñez
Advances in anatomic pathology, 19(3), 140-151 (2012-04-14)
PAX 8 is a transcription factor involved in the regulation of organogenesis of the thyroid gland, kidney, and Müllerian system. Recent studies have shown that, among tumors, PAX 8 is commonly expressed in epithelial tumors of the thyroid and parathyroid
Ping Zhang et al.
Pathology international, 56(5), 240-245 (2006-05-04)
Thyroid transcription factor 1 (TTF1), thyroid transcription factor 2 (TTF2) and paired box gene 8 (Pax8) are demonstrated to play a crucial role for the differentiation and organogenesis of thyroid follicular cells. Their roles in thyroid carcinogenesis are not very

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