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Merck
모든 사진(1)

주요 문서

52194

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate–Dextran

average mol wt 500,000

동의어(들):

TRITC Dextran, TRITC-Dextran 500, TRITC-Dextran

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About This Item

MDL number:
UNSPSC 코드:
12352116
NACRES:
NA.32

생물학적 소스

synthetic

Quality Level

양식

powder or crystals

분자량

average mol wt 500,000

라벨링 범위

0.001-0.008 mol/mol TRITC glucose

형광

λex 550 nm; λem 575 nm±5 nm in 0.1 M Tris pH 8.0

응용 분야

cell analysis

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일반 설명

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 500, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.

애플리케이션

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 500) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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문서 라이브러리 방문

Margaret Clarke et al.
Journal of cell science, 115(Pt 14), 2893-2905 (2002-06-26)
The vacuolar H(+)-ATPase (V-ATPase) is a multi-subunit enzyme that plays important roles in eukaryotic cells. In Dictyostelium, it is found primarily in membranes of the contractile vacuole complex, where it energizes fluid accumulation by this osmoregulatory organelle and also in
Thea van der Wijk et al.
The Journal of biological chemistry, 278(41), 40020-40025 (2003-07-23)
Osmotic swelling of Intestine 407 cells leads to an immediate increase in cell surface membrane area as determined using the fluorescent membrane dye FM 1-43. In addition, as measured by tetramethylrhodamine isothiocyanate (TRITC)-dextran uptake, a robust (>100-fold) increase in the
Alexa Patzelt et al.
Journal of controlled release : official journal of the Controlled Release Society, 246, 174-182 (2016-09-20)
More and more investigations confirm that nanoparticles are incapable of overcoming the intact skin barrier in vivo. Do nanoparticles still have a future in dermal drug delivery? Unlike many other topically applied substances, nanoparticles have not been reported to utilize
Ngo Bich Nga Nathalie Tran et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 116, 12-16 (2016-10-25)
Hair follicle research is currently focused on the development of drug-loaded nanocarriers for the targeting of follicular structures in the treatment of skin and hair follicle-related disorders. In the present study, a dual-label nanocarrier system was implemented in which FITC-labeled
Matthias Osswald et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(24), 6078-6087 (2016-08-16)
The role of blood-brain barrier (BBB) integrity for brain tumor biology and therapy is a matter of debate. We developed a new experimental approach using in vivo two-photon imaging of mouse brain metastases originating from a melanoma cell line to

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