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Merck
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Key Documents

64255

Sigma-Aldrich

Methylenediphosphonic acid

for molecular studies & mass spectrometry

동의어(들):

MDP, Medronic acid

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About This Item

Linear Formula:
CH2[P(O)(OH)2]2
CAS Number:
Molecular Weight:
176.00
Beilstein:
1708494
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.52

Quality Level

형태

powder

mp

197-199 °C (lit.)
201-205 °C

저장 온도

2-8°C

SMILES string

OP(O)(=O)CP(O)(O)=O

InChI

1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)

InChI key

MBKDYNNUVRNNRF-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.

애플리케이션

Suitable for
  • preparation of analogs of natural di- and tri-phosphates
  • mass spectrometry studies as analytical standard
  • molecular studies related to inflammation

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리 방문

H F Kung et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 19(9), 1027-1031 (1978-09-01)
Bidentate monophosphates--phosphonoacetate (PAA), 2-phosphonoproprionate (PPA), 2-methyl-2-phosphonoproprionate (MPPA), and carbamyl phosphate (CAP)--which are pyrophosphate analogs, were successfully labeled with Sn(II)-reduced [99mTc] pertechnetate in high yield (greater than 95%). Biodistribution studies show that these Tc-99m-labeled monophosphates do localize in bone. At 2
T G Rudd et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 18(9), 872-876 (1977-09-01)
The biologic and imaging characteristics of Tc-99m MDP and Tc-99m PPi were compared in animals and patients using freeze-dried bone-imaging kits. Biodistribution data in rabbits showed Tc-99m MDP had slightly higher bone uptake, significantly lower blood levels, and faster urinary
R. Engel
Chemical Reviews, 77, 349-349 (1977)
Phosphonic acid analogs of nucleoside phosphates. I. The synthesis of 5'-adenylyl methylenediphosphonate, a phosphonic acid analog of ATP
Myers TC et al
Journal of the American Chemical Society, 85, 3292-3295 (1963)
J.A. Stock
The Journal of Organic Chemistry, 44, 3997-3997 (1979)

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