A5963

Anti-c-Myc−Alkaline Phosphatase antibody, Mouse monoclonal

clone 9E10, purified from hybridoma cell culture

• 동의어(들): Anti-c-Myc, Monoclonal Anti-c-Myc−Alkaline Phosphatase antibody produced in mouse
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: alkaline phosphatase conjugate
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 9E10, monoclonal
• 형태: buffered aqueous glycerol solution
• 종 반응성: human
• 기술: ELISA: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 1:100 using a myc-tagged fusion protein.
• 동형: IgG1
• UniProt 수납 번호: P01106
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MYC(4609)

설명

일반 설명

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-myc gene encodes for a protein of 62kDa called p62^c-myc is associated mainly with cell nuclei.

면역원

synthetic peptide of the human p62^c-Myc protein.

애플리케이션

Anti-c-Myc-Alkaline Phosphatase antibody has been used in

• enzyme linked immunosorbent assay (ELISA)
• immunohistochemical labeling
• immunostaining
• western blotting

Monoclonal Anti-c-Myc-Alkaline Phosphatase antibody can be used for western blot assays at 1:100, using myc-tagged fusion proteins. The antibody can also be used for immunohistochemical applications.

생화학적/생리학적 작용

The c-myc oncogene product(p62^c-myc) exerts normal and oncogenic cellular functions. Elevated level of c-myc protein in malignant tissues when compared with normal tissue, but with the unexpected finding of a cytoplasmic accumulation of the protein in these tumors.

물리적 형태

Solution in 0.05 M Tris buffer, containing 1% bovine serum albumin, 1 mM MgCl₂, 50% glycerol, and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)