추천 제품
![[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt ≥95% (HPLC), solid](/deepweb/assets/sigmaaldrich/product/images/296/089/259ad19e-25e1-4604-9077-8d4dbea518b6/640/259ad19e-25e1-4604-9077-8d4dbea518b6.jpg)
생물학적 소스
rabbit
결합
agarose conjugate
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
human
분석물 화학적 분류
proteins (c-Myc)
기술
affinity chromatography: suitable
immunoprecipitation (IP): suitable
용량
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
UniProt 수납 번호
저장 온도
2-8°C
유전자 정보
human ... MYC(4609)
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일반 설명
The human c-Myc proto-oncogene belongs to MYC oncogene family and is the human cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses. c-Myc gene is localized on human chromosome 8q24.21. The two major domains of include the N-terminal box regions and the C-terminal basic-region with helix-loop-helix/leucine-zipper motif.
특이성
Anti-c-Myc recognizes an epitope located on c-Myc tagged fusion proteins.
면역원
synthetic peptide of the human p62c-Myc protein.
애플리케이션
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit has been used in:
- chromatin immunoprecipitation (ChIP)
- co-immunoprecipitation
- western blotting
- immunofluorescence
- immunoprecipitation
생화학적/생리학적 작용
c-Myc proto-oncogene increased expression is observed in a variety of human tumors. Amplification of Myc gene locus is observed in angiosarcomas and translocation is implicated in Burkitt′s lymphoma. c-Myc is a master regulator and targets a wide variety of metabolic events. An epitope located within amino acid residues 410-419 (EQKLISEEDL) of human c-Myc has been widely used as a tag in many expression vectors, enabling the expression of proteins as c-Myc tagged fusion proteins. Anti-c-Myc agarose is useful in the purification of expressed c-Myc tagged fusion proteins in bacterial lysates or transfected cells.
물리적 형태
Suspension of beaded agarose (1:1 v/v) in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
저장 및 안정성
For continuous use and extended storage, store at 2 °C to 8 °C. Do not freeze.
면책조항
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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