F124

Furafylline

≥98% (HPLC), powder, caffeine inhibitor

• 동의어(들): 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
• 실험식(Hill 표기법): C₁₂H₁₂N₄O₃
• CAS Number: 80288-49-9
• Molecular Weight: 260.25
• MDL number: MFCD00153799
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24278813
• NACRES: NA.77

속성

• product name: Furafylline, ≥98% (HPLC)
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• mp: 274-275 °C
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CN1C(=O)N(Cc2ccco2)c3nc(C)[nH]c3C1=O
• InChI: 1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)
• InChI key: KGQZGCIVHYLPBH-UHFFFAOYSA-N
• 유전자 정보: human ... CYP1A2(1544)

설명

생화학적/생리학적 작용

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

Furafylline is a methyl xanthine derivative with longer duration of action than theophylline and an inhibitor of cytochrome P4501A2.

특징 및 장점

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)