추천 제품
생물학적 소스
human
Quality Level
재조합
expressed in NSO cells
분석
≥97% (SDS-PAGE)
형태
lyophilized powder
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... GPC3(2719)
일반 설명
Glypican-3, a cell surface protein, is highly expressed in hepatocellular carcinoma (HCC) and few other human cancers including melanoma. It is a heparan sulfate proteoglycan and is present on the cell surface. Under non-reducing conditions in SDS-PAGE, the glycanated glypican 3 appears as a smear with an apparent molecular mass of 60 - 100 kDa†
생화학적/생리학적 작용
Sulfate proteoglycan attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor. Regulates cell survival and inhibits cell proliferation during normal development. Potential use as marker for early disease detection.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in PBS containing 50 μg of bovine serum albumin per 1 μg of cytokine.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Yu-Liang Wang et al.
World journal of gastroenterology, 18(19), 2408-2414 (2012-06-02)
To investigate the diagnostic value of glypican-3 (GPC3) and its relationship with hepatocellular carcinoma (HCC) recurrence after liver transplantation. HCC tissue samples (n = 31) obtained from patients who had undergone liver transplantation were analyzed. GPC3 mRNA and protein expression
Restriction enzyme cleavage of UV-irradiated DNA: a comparison of far-UV and mid-UV wavelengths.
S P Moore et al.
Photochemistry and photobiology, 45(2), 253-263 (1987-02-01)
Shiro Suzuki et al.
Human vaccines & immunotherapeutics, 10(2), 338-343 (2013-11-21)
Carcinoembryonic antigen glypican-3 (GPC3) is expressed by>40% of ovarian clear cell carcinoma (CCC) and is a promising immunotherapeutic target. We previously reported the safety of and immunological and clinical responses to a GPC3-derived peptide vaccine in a phase I clinical
문서
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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