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Merck
모든 사진(1)

Key Documents

L9151

Sigma-Aldrich

Lys-Lys-Lys-Lys-Lys

≥55% peptide basis, Bioreagent

동의어(들):

Lys5, Pentalysine

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About This Item

실험식(Hill 표기법):
C30H62N10O6
CAS Number:
Molecular Weight:
658.88
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Lys-Lys-Lys-Lys-Lys, ≥55% peptide basis

형태

powder

구성

Peptide content, ~60%

농도

≥55% (peptide)

색상

white

저장 온도

−20°C

SMILES string

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)

InChI key

IXPHOHNWDLRFJH-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys-Lys

생화학적/생리학적 작용

Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids.
T M Lohman et al.
Biochemistry, 19(15), 3522-3530 (1980-07-22)
Dan Zhao et al.
Journal of neuroinflammation, 14(1), 234-234 (2017-12-05)
It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inflammatory pathway, but the role of cholinergic signaling and α7nAChR in chronic stress has not
M Roux et al.
European biophysics journal : EBJ, 16(5), 267-273 (1988-01-01)
The interaction of cationic pentalysine with phospholipid membranes was studied by using phosphorus and deuterium Nuclear Magnetic Resonance (NMR) of headgroup deuterated dimyristoyl phosphatidylcholine (DMPC) and dimyristoyl phosphatidylserine (DMPS). In the absence of pentalysine, some of the deuterium and phosphorus
Marisa Claudia Alvarez et al.
Clinical epigenetics, 10(1), 139-139 (2018-11-10)
In the present study, we investigated the molecular mechanisms underlying the pro-apoptotic effects of quercetin (Qu) by evaluating the effect of Qu treatment on DNA methylation and posttranslational histone modifications of genes related to the apoptosis pathway. This study was
Fabiana Perocchi et al.
Nucleic acids research, 35(19), e128-e128 (2007-09-28)
Recent transcription profiling studies have revealed an unanticipatedly large proportion of antisense transcription across eukaryotic and bacterial genomes. However, the extent and significance of antisense transcripts is controversial partly because experimental artifacts are suspected. Here, we present a method to

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