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Merck
모든 사진(5)

문서

N3014

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide hydrate

suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast

동의어(들):

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide

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About This Item

실험식(Hill 표기법):
C21H27N7O14P2 · xH2O
CAS Number:
Molecular Weight:
663.43 (anhydrous basis)
MDL number:
UNSPSC 코드:
41106305
eCl@ss:
39200202
PubChem Substance ID:
NACRES:
NA.55

생물학적 소스

yeast

분석

≥96.5% (HPLC)
≥96.5% (spectrophotometric assay)

형태

powder

분자량

Mw 663.43 g/mol

기술

cell culture | mammalian: suitable

불순물

≤3% Acetone

색상

white to off-white

solubility

H2O: 50 mg/mL

저장 온도

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

유전자 정보

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애플리케이션


  • Spectroelectrochemical Enzyme Sensor System for Acetaldehyde Detection in Wine.: This study explores the development of a novel sensor system using β-Nicotinamide adenine dinucleotide hydrate to detect acetaldehyde in wine, enhancing the accuracy of wine quality control (Ibáñez et al., 2022).

  • Screening of Lactate Dehydrogenase Inhibitor from Bioactive Compounds in Natural Products by Electrophoretically Mediated Microanalysis.: The research utilizes β-Nicotinamide adenine dinucleotide hydrate to screen potential lactate dehydrogenase inhibitors, which could lead to new therapeutic agents for diseases such as cancer (Li et al., 2021).

  • Combination of NAD(+) and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress.: This research highlights the neuroprotective effects of NAD+ and NADPH in stroke models, emphasizing the potential therapeutic applications of β-Nicotinamide adenine dinucleotide hydrate in neuroprotection (Huang et al., 2018).

생화학적/생리학적 작용

Electron acceptor

포장

Packaged by solid weight.

기타 정보

Meets or exceeds NRC specifications.
This is the common form of NAD.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
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Mice overexpressing the mitotic checkpoint kinase gene BubR1 live longer, whereas mice hypomorphic for BubR1 (BubR1(H/H)) live shorter and show signs of accelerated aging. As wild-type mice age, BubR1 levels decline in many tissues, a process that is proposed to

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