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Merck
모든 사진(4)

Key Documents

P9528

Sigma-Aldrich

Polyuridylic acid potassium salt

동의어(들):

Poly(U) potassium salt

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
41106305
NACRES:
NA.51

분석

≥98% (TLC)

Quality Level

형태

lyophilized powder

solubility

water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless

저장 온도

−20°C

InChI

1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

InChI key

DJJCXFVJDGTHFX-XVFCMESISA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.

제조 메모

Prepared from UDP using polynucleotide phosphorylase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Soren Nielsen et al.
Science (New York, N.Y.), 340(6140), 1577-1580 (2013-07-03)
Gene expression in organisms involves many factors and is tightly controlled. Although much is known about the initial phase of transcription by RNA polymerase III (Pol III), the enzyme that synthesizes the majority of RNA molecules in eukaryotic cells, termination
Liam M Longo et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(27), 15731-15739 (2020-06-21)
De novo emergence demands a transition from disordered polypeptides into structured proteins with well-defined functions. However, can polypeptides confer functions of evolutionary relevance, and how might such polypeptides evolve into modern proteins? The earliest proteins present an even greater challenge
Tiago Antonio de Souza et al.
PloS one, 7(2), e32305-e32305 (2012-03-03)
Plant pathogenic bacteria utilize an array of effector proteins to cause disease. Among them, transcriptional activator-like (TAL) effectors are unusual in the sense that they modulate transcription in the host. Although target genes and DNA specificity of TAL effectors have
A Maxwell Burroughs et al.
Nucleic acids research, 40(4), 1424-1437 (2011-11-08)
Recent research hints at an underappreciated complexity in pre-miRNA processing and regulation. Global profiling of pre-miRNA and its potential to increase understanding of the pre-miRNA landscape is impeded by overlap with highly expressed classes of other non coding (nc) RNA.
Yann Fichou et al.
Frontiers in neuroscience, 13, 1339-1339 (2020-01-11)
The aggregation of the human tau protein into neurofibrillary tangles is directly diagnostic of many neurodegenerative conditions termed tauopathies. The species, factors and events that are responsible for the initiation and propagation of tau aggregation are not clearly established, even

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