추천 제품
생물학적 소스
plant (Silybum marianum)
형태
powder
기술
toxicology assay: suitable
응용 분야
microbiology
저장 온도
−20°C
InChI
1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3
InChI key
SEBFKMXJBCUCAI-UHFFFAOYSA-N
일반 설명
Silymarin is a flavonolignan, obtained from milk thistle (Silybum marianum) plant.
애플리케이션
Silymarin has been used to study:
- its in vitro antiviral, antibacterial, antifungal activities and cytotoxicity
- its effect of silymarin on bladder contractions in cyclophosphamide (CYP)-induced cystitis rat model
- its effect on liver toxication induced by Fumonisin B1 in mice
생화학적/생리학적 작용
Silymarin is originally known to protect liver from various toxic agents and is used in treating hepatitis and cirrhosis. Silymarin possesses many biological actions such as antifibrotic, anti-lipid peroxidative, anti-inflammatory, immunomodulatory and membrane stabilizing. Silymarin also aids in liver regeneration.
Silymarin provides cardioprotective activity against ischemia-reperfusion induced myocardial infarction in rats.
Silymarin was shown to protect the liver from the cytotoxic effects of anti-tuberculosis drugs by decreasing serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) levels. This effect was related to the anti-oxidant effects of silymarin.
기타 정보
Mixture of anti-hepatotoxic flavonolignans from the fruit of Silybum marianum.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Nuriye Ezgi Bektur Aykanat et al.
Pharmacological reports : PR, 72(1), 199-207 (2020-02-06)
14 million people are diagnosed with new cancer and approximately 8 million people die from cancer every year. Hepatocellular carcinoma is the most common type of liver cancer and covers almost 5-6% of cancer deaths worldwide. Silybum marianum, a plant
Multitargeted therapy of cancer by silymarin
Ramasamy K and Agarwal R
Cancer letters, 269(2), 352-362 (2008)
Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in mice
Sozmen M, et al.
Journal of Veterinary Science, 15(1), 51-60 (2012)
Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals.
Eminzade, S.
Nutrition & Metabolism, 5, 18-18 (2008)
Vieri Piazzini et al.
Molecules (Basel, Switzerland), 24(9) (2019-05-06)
Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with d-α-tocopherol polyethylene glycol 1000 succinate (vitamin E TPGS) were prepared using
문서
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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