추천 제품
분석
≥98% (HPLC)
형태
solid
solubility
DMSO: 26 mg/mL
저장 온도
room temp
SMILES string
Cc1ccc(C)c(NS(=O)(=O)c2cc(ccc2C)C(=O)Nc3ccccc3-c4ccccc4)c1
InChI
1S/C28H26N2O3S/c1-19-13-14-20(2)26(17-19)30-34(32,33)27-18-23(16-15-21(27)3)28(31)29-25-12-8-7-11-24(25)22-9-5-4-6-10-22/h4-18,30H,1-3H3,(H,29,31)
InChI key
BWWPVIRXNOWQSI-UHFFFAOYSA-N
애플리케이션
SF-22 may be used in NPY Y2 receptor-mediated studies.
생화학적/생리학적 작용
Radioligand studies reveal that SF-22 also targets 5-HT2B and 5-HT6 serotonin receptors and dopamine transporter.1
SF-22 is a potent, selective NPY Y2 receptor antagonist; highly brain-penetrant
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Shaun P Brothers et al.
Molecular pharmacology, 77(1), 46-57 (2009-10-20)
The role of neuropeptide Y Y2 receptor (Y2R) in human diseases such as obesity, mood disorders, and alcoholism could be better resolved by the use of small-molecule chemical probes that are substantially different from the currently available Y2R antagonist, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide)
Xinghua Feng et al.
Cell calcium, 56(6), 446-456 (2014-10-01)
Mucolipin synthetic agonist 1 (ML-SA1) was recently identified to activate mammalian TRPML channels and shown to alleviate lipid accumulation in lysosomes of cellular models of lysosome storage diseases, mucolipidosis type IV (MLIV) and Niemann-Pick's disease type C (NPC). Owning to
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