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MilliporeSigma
모든 사진(4)

주요 문서

S6508

Sigma-Aldrich

Sodium orthovanadate

≥90% (titration)

동의어(들):

Trisodium vanadate

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크기 선택

10 G
$40.40
50 G
$138.00
250 G
$527.25

$40.40


출고 가능일April 11, 2025세부사항


벌크 견적 요청

크기 선택

보기 변경
10 G
$40.40
50 G
$138.00
250 G
$527.25

About This Item

Linear Formula:
Na3VO4
CAS Number:
Molecular Weight:
183.91
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

$40.40


출고 가능일April 11, 2025세부사항


벌크 견적 요청

생물학적 소스

synthetic (organic)

분석

≥90% (titration)

양식

crystalline powder

반응 적합성

reagent type: catalyst
core: vanadium

색상

white to off-white

mp

850-866 °C (lit.)

solubility

H2O: soluble

SMILES string

[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChI key

IHIXIJGXTJIKRB-UHFFFAOYSA-N

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애플리케이션

Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase.26 It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.27

생화학적/생리학적 작용

Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.
Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25

특징 및 장점

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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