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Merck
모든 사진(1)

Key Documents

SAB3701079

Sigma-Aldrich

Anti-Mouse IgG (H+L) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

secondary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

mouse

농도

1.95 mg/mL

기술

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

일반 설명

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical (called Fab fragments) and contain the antigen-binding activity. The third fragment (called Fc fragment) does not possess antigen-binding activity, but binds to cells and effector molecules. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.

특이성

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Rabbit Serum, Mouse IgG and Mouse Serum.

면역원

Mouse IgG whole molecule

물리적 특성

Antibody format: IgG

물리적 형태

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Human placental Fc receptors and the transmission of antibodies from mother to fetus.
Simister NE and Story CM
Journal of Reproductive Immunology (1997)
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences (2007)

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