추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 19 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PARK7(11315)
일반 설명
Anti-PARK7 Antibody detects endogenous levels of total PARK7 protein.
면역원
The antiserum was produced against synthesized peptide derived from human PARK7.
Immunogen Range: 61-110
Immunogen Range: 61-110
애플리케이션
Anti-PARK7 antibody produced in rabbit is suitable for indirect ELISA and western blot applications.
생화학적/생리학적 작용
PARK7 is a member of novel glyoxalase family. It exerts mitochondrial activity. It has been suggested that PARK7 may act as an antioxidant and/or a molecular chaperone. It may also detoxify aggressive metabolic aldehyde by-products. It helps in stabilizing mitochondria during cellular stress. Alteration in gene function affects neurodegeneration, which leads to the autosomal recessive early-onset parkinsonism.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Jacek R Wiśniewski et al.
Journal of proteome research, 15(7), 2321-2326 (2016-06-15)
Proteomics and other protein-based analysis methods such as Western blotting all face the challenge of discriminating changes in the levels of proteins of interest from inadvertent changes in the amount loaded for analysis. Mass-spectrometry-based proteomics can now estimate the relative
Yusuke Toyoda et al.
Biology open, 3(8), 777-784 (2014-07-27)
Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. One of the genes linked with the onset of Parkinson's disease, DJ-1/PARK7, belongs to a novel glyoxalase family and influences mitochondrial activity. It has been assumed
V Bonifati et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 24(3), 159-160 (2003-11-05)
Four chromosomal loci ( PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. We mapped the PARK7 locus to chromosome 1p36 in a large family from a genetically isolated population in the Netherlands, and confirmed
Vincenzo Bonifati et al.
Science (New York, N.Y.), 299(5604), 256-259 (2002-11-26)
The DJ-1 gene encodes a ubiquitous, highly conserved protein. Here, we show that DJ-1 mutations are associated with PARK7, a monogenic form of human parkinsonism. The function of the DJ-1 protein remains unknown, but evidence suggests its involvement in the
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